Diseases of our
nervous system can be difficult to understand and challenging to live with. The
body’s nervous system is made up of the brain, spinal cord, and peripheral
nerves. Neurosurgeons provide care for a range of disorders of these organs. To
our good fortune, we have seen dramatic growth in our understanding of the
nervous system and its diseases, as well as science fiction-like technological
advancements available to the specialists who treat nervous system problems. This
may be most true in the subspecialty of functional neurosurgery.
What is “functional”
neurosurgery? Just as it sounds, functional neurosurgery is a super-specialized
field which treats degenerative and idiopathic (i.e. without known cause)
nervous system diseases which compromise an individual’s everyday function.
This generally includes movement disorders, pain syndromes, and epilepsy. As a
group, functional disorders have been traditionally challenging to treat. Those
who suffer with them are usually under the care of a neurologist who is
familiar with the patient, the history of their illness, and their treatments.
A neurosurgeon with modern functional expertise can play an important role in
helping make neurologists’ treatments more efficient and effective.
Deep brain
stimulation (DBS) gets the most attention of any current technique in
functional neurosurgery. This therapy, where deep brain structures are
electrically stimulated, has made significant impact particularly on the
treatment of movement disorders. Movement disorders are neurological diseases
which are characterized by the presence of abnormal movement or muscle tone,
absence of normal movement, or combination of the two. The most well-known
movement disorder is Parkinson’s Disease, but other noteworthy disorders
include essential tremor, dystonia, spasticity, and chorea. Those with
Parkinson’s Disease suffer from rigidity of their limbs, tremor, and a
difficulty and slowness with normal movements. Contemporary medications can
dramatically reduce these symptoms, but over time these drugs begin to lose
efficacy and come with side effects. DBS is now proven as an effective procedure
for reducing symptoms of Parkinson’s Disease and essential tremor, and
potentially lowering the amount of medication needed to treat both disorders.
DBS is a minimally-invasive surgery usually performed with the patient awake
under light sedation. The surgeon uses a computerized guidance system and
high-resolution MRI to implant small electrodes into the deep brain target with
sub-millimeter accuracy. The patient recovers from surgery quickly and usually
goes home from the hospital the day after the procedure.
The functional
neurosurgeon also treats pain syndromes, including trigeminal neuralgia, cancer
pain, and chronic low back and leg pain. Various functional procedures may be
helpful for these patients. For example, trigeminal neuralgia is a facial pain
syndrome caused by abnormal activity of the trigeminal nerve (the nerve that
transmits sensation from the face). This can be a disabling problem, which in
its most severe form can make even eating and talking very painful. Neurologists
offer medications that may significantly reduce the frequency and severity of
pain attacks. When pain continues despite medicines, a neurosurgeon with
functional expertise may suggest surgical microvascular decompression of the
nerve, stereotactic radiosurgery to the nerve, or targeted injections of
substances designed to quiet nerve activity. Stereotactic radiosurgery is a
non-invasive procedure in which the neurosurgeon uses computer guidance to
deliver highly focused beams of radiation. The decision as to which treatment
is best for trigeminal neuralgia is complicated and done on an individual
basis. This decision should be undertaken with a neurosurgeon experienced with
the disease and all forms of therapy.
Current functional
neurosurgery makes a significant impact on the lives of those who suffer with
these chronic, debilitating conditions. Research is rapidly improving our
knowledge of brain function, our understanding of these and other complicated
neurological diseases, and advancing avenues of treatment, such as: gene and
molecular therapy. With that in mind, the future of functional neurosurgery is
extraordinarily bright.